⚑ Longevity & Wellness · Apgujeong Hana Clinic

NAD+ IV Therapy Seoul — cellular energy & anti-ageing infusion in English.

Medical-grade NAD+ IV therapy at Apgujeong Hana Clinic, Apgujeong, Gangnam. Board-certified specialist — personalised NAD+ infusion protocols for energy, cognitive function, anti-ageing and metabolic health. All in English.

βœ… Medical Grade NAD+ βœ… English-Friendly βœ… Medically Supervised βœ… Personalised Protocol
50% NAD+ decline from age 40 to 60
100% Bioavailability — IV vs oral supplements
500+ Enzymes dependent on NAD+ for function
2–4 hr Infusion time — comfortable reclining chair
βœ“ Medical-Grade NAD+
βœ“ Medically Supervised
βœ“ Personalised Dosing
βœ“ English-Friendly
Meet Our Doctors →
What Is NAD+

NAD+ — the molecule at the centre of cellular energy and ageing.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell in the body. It is essential for hundreds of metabolic reactions — most critically, the production of ATP (cellular energy), the activation of sirtuins (longevity-associated proteins), DNA repair mechanisms and the regulation of circadian rhythm. Without adequate NAD+, these processes slow down — and the effects are felt as fatigue, brain fog, reduced resilience and accelerated biological ageing.

The critical problem is that NAD+ levels decline dramatically with age. By the time most adults reach 60, their cellular NAD+ levels are approximately 50% of what they were at 40. This decline is not uniform — it is driven and accelerated by chronic inflammation, metabolic dysfunction, alcohol consumption, sleep deprivation and oxidative stress. The result is a progressive reduction in cellular energy production and repair capacity that underlies much of what we experience as "normal" ageing.

NAD+ IV therapy delivers NAD+ directly into the bloodstream — bypassing the digestive system limitations of oral NAD+ precursors such as NMN and NR, which must be converted to NAD+ through multiple metabolic steps. IV administration provides 100% bioavailability and produces measurable increases in cellular NAD+ levels that oral supplementation cannot replicate at equivalent doses.

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Restores Cellular Energy
NAD+ is essential for ATP production — the cellular energy currency. Replenishing NAD+ directly supports mitochondrial function and cellular energy generation.
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Activates Longevity Proteins
NAD+ activates sirtuins — a family of proteins strongly associated with longevity in research. Sirtuins regulate DNA repair, inflammation and metabolic health — all key drivers of biological ageing.
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Supports Brain Function
The brain is one of the most metabolically active organs — and one of the most sensitive to NAD+ decline. NAD+ supports cognitive function, neuroplasticity and protection against neurodegeneration.
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Enhances DNA Repair
PARP enzymes — which repair DNA damage — are entirely dependent on NAD+. Inadequate NAD+ impairs DNA repair, allowing damage to accumulate and accelerate cellular ageing.
Clinical Benefits

What NAD+ IV therapy can do for you.

The clinical benefits of NAD+ IV therapy are supported by a growing body of research — from animal studies demonstrating lifespan extension to human clinical trials showing improvements in energy, cognitive function and metabolic health. Individual responses vary — most patients notice benefits within 1–3 sessions.

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Increased Energy & Vitality
The most commonly reported benefit — improved cellular energy production translates into significantly higher sustained energy levels, reduced fatigue and improved physical endurance. Many patients describe the effect as feeling "years younger" in terms of daily energy.
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Cognitive Clarity & Focus
Improved mental clarity, sharper focus and reduced brain fog are consistently reported after NAD+ infusion — particularly by patients who had experienced age-related or stress-related cognitive decline. NAD+ supports neuronal energy metabolism and neurotransmitter function.
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Improved Sleep Quality
NAD+ plays a central role in circadian rhythm regulation — the body's internal clock. Replenishing NAD+ levels supports more consistent circadian function, which translates into improved sleep quality and more refreshed waking. Particularly relevant for jet-lagged executives and shift workers.
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Exercise Performance & Recovery
Improved mitochondrial function from NAD+ replenishment enhances both exercise capacity and post-exercise recovery. Athletes and active individuals report improved endurance and faster muscle recovery between sessions.
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Anti-Ageing & Longevity
Through sirtuin activation, DNA repair support and mitochondrial function improvement, NAD+ therapy targets three of the most established hallmarks of biological ageing. Regular NAD+ infusion is one of the most evidence-based longevity interventions currently available.
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Metabolic Health Support
NAD+ plays a key role in glucose metabolism and insulin sensitivity. Research shows that NAD+ replenishment improves markers of metabolic health — particularly relevant for patients with insulin resistance, prediabetes or metabolic syndrome.
NAD+ Protocols

Our NAD+ infusion protocols — personalised for your goals.

At Apgujeong Hana Clinic, NAD+ therapy is not a fixed dose for every patient. Your protocol is designed based on your age, health status, biological age assessment results, specific goals and previous NAD+ therapy experience. Dr. Shin selects the appropriate protocol and monitors your response throughout each session.

Protocol 1
Introductory NAD+ Infusion
250mg · 2–3 hours · First session
Recommended for first-time NAD+ IV therapy patients. Lower dose allows assessment of tolerance and individual response. Most patients experience clear energy and cognitive improvements within 24 hours. Single session or beginning of a loading protocol.
Protocol 2
Standard Longevity Protocol
500mg · 3–4 hours · Monthly maintenance
The most commonly prescribed protocol for longevity and anti-ageing. Suitable for patients who have completed an introductory session. Monthly infusions maintain elevated NAD+ levels between sessions. Often combined with glutathione push at the end of infusion.
Protocol 3
High-Dose Loading Protocol
750–1000mg · 4–6 hours · 3–5 sessions loading
For patients with significant fatigue, cognitive decline or metabolic dysfunction. Loading phase of 3–5 sessions over 1–2 weeks to rapidly replenish NAD+ stores, followed by monthly maintenance infusions. Most dramatic subjective improvement in energy and cognition typically seen with this protocol.
How It Works

Your NAD+ IV therapy session, step by step.

1
Consultation & Protocol
Initial consultation with Dr. Shin — health history, symptoms, goals and any previous NAD+ therapy discussed in English. Protocol selected and explained. Blood pressure and vitals checked before infusion.
2
IV Cannula Placement
Small IV cannula placed in the forearm vein — quick and minimally uncomfortable. NAD+ solution prepared at the prescribed dose and concentration. You recline comfortably in our IV therapy chair for the duration.
3
Monitored Infusion
NAD+ infused slowly over 2–4 hours at a rate titrated to your comfort. Our team monitors you throughout — rate adjusted if any discomfort occurs. Mild flushing or a warm sensation is common and expected during infusion.
4
Post-Infusion & Plan
Brief observation after infusion completion. Most patients feel well immediately and can return to normal activities. Next session scheduled. Oral NMN/NR supplement recommended for maintenance between sessions.
FAQ

Your questions answered.

More questions about NAD+ IV therapy? WhatsApp our English-friendly team at Apgujeong Hana Clinic.

The IV cannula placement is similar to a standard blood draw — a brief, minor discomfort. During the infusion itself, the most commonly reported sensation is mild flushing, warmth or a slight chest tightness — particularly at higher infusion rates. These sensations are normal and not harmful. Our team adjusts the infusion rate to keep these sensations minimal and manageable. Slow infusion is the key to comfort — we never rush the rate.
Most patients notice improvements in energy and mental clarity within 24–48 hours of their first infusion. Some patients feel effects more immediately — a clarity or lightness during or shortly after the session. Cognitive benefits typically become more pronounced after 2–3 sessions. Patients on a loading protocol often report the most dramatic improvements — with energy and cognitive function notably improved by the end of the loading phase.
For most patients, a monthly maintenance infusion is appropriate after completing an initial loading phase. For patients with significant fatigue or cognitive symptoms, a loading protocol of 3–5 sessions over 1–2 weeks followed by monthly maintenance produces the most significant and sustained improvement. Your specialist designs your specific protocol based on your goals and response to initial sessions.
NAD+ IV therapy has an excellent safety profile. The most common side effects during infusion are mild flushing, warmth, chest tightness or nausea — all of which resolve immediately when the infusion rate is slowed. Serious adverse events are extremely rare. A thorough medical history review is performed before your first infusion. NAD+ therapy is not appropriate for patients with certain conditions — your specialist confirms safety before prescribing.
Yes — oral NAD+ precursors (NMN or NR) are recommended as a complement to IV therapy, particularly between sessions. They help maintain elevated NAD+ levels between monthly infusions and extend the benefit period. Your specialist will advise on appropriate dosing and timing. Dr. Shin can also advise on the quality and dosing of available NMN and NR supplements if you wish to begin oral supplementation alongside IV therapy.
WhatsApp (+82 10-2950-7551) is the fastest way. You can also call 02) 3443-7550 or book via Naver Booking. Same-week appointments are usually available. We are at 328 Apgujeong-ro, KFC Building 3F, Gangnam-gu, Seoul. Mon–Fri 09:00–19:00, Sat 09:00–13:00. NAD+ sessions are 2–4 hours — morning appointments allow you to recover and return to normal activities by afternoon.

Book your NAD+ IV therapy in Seoul.

Medical-grade NAD+ infusion at Apgujeong Hana Clinic, Gangnam. Personalised protocols. Medically supervised. English throughout. Same-week appointments.

βœ“ Medical-Grade NAD+
βœ“ Personalised Protocol
βœ“ Medically Supervised
βœ“ English-Friendly